Job Summary: We are a fast-growing research and services division of WuXi AppTec, advancing innovative drug discovery platforms integrating chemistry and biology. We are seeking a motivated and collaborative ASMS Scientist to support affinity selection mass spectrometry (ASMS) workflows for small molecule and peptide discovery. This role will contribute to assay execution, data analysis, and scientific reporting, supporting both internal and client-driven programs.
Responsibilities
Independently operate, maintain, and troubleshoot mass spectrometry instrumentation
Develop and execute ASMS assays — primary screening, hit confirmation, affinity ranking
Drive assay method development and orthogonal cross-validation
Analyze, interpret, and report quantitative MS data; deliver client-ready scientific reports
Present scientific data to clients; maintain client technical relationships
Qualifications
PhD in Analytical Chemistry, Biophysics, Biochemistry, or related discipline, with 2+ years of ASMS relevant experience; or Master with 5+ years of ASMS relevant experience.
Deep, hands-on, independent operation and method development on modern high-resolution MS systems
Demonstrated experience designing and running ASMS assays for small-molecule binding
Proficiency in pooled-library screening, hit deconvolution, and quantitative MS data analysis
Working knowledge of orthogonal biophysics techniques (SPR, NMR, DSF, ITC)
WuXi AppTec is a trusted partner and contributor to the pharmaceutical and life sciences industries, providing R&D and manufacturing services that help advance healthcare innovation. With operations across Asia, Europe, and North America, we offer integrated, end-to-end services through our unique CRDMO (Contract Research, Development, and Manufacturing Organization) platform. We are privileged to work alongside partners across 30+ countries, supporting their efforts to bring breakthrough treatments to patients. Guided by ou...